Deoxyribonucleic acid and ribonucleic acid
This Editorial Guide is used for Education Purposes Only. It is used in the Authoring Courses and Certifications. It is based on the January 2026 Editorial Guide.
Modeling - Ribonucleic acid of X organism
Parent concept
Most distal appropriate descendant of 118248003 |Microbial ribonucleic acid (substance)|
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: <726711005 |Disposition (disposition)|
While the allowed range is broader, substance concepts should only use <726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..*
Naming Guidelines - Ribonucleic acid of X organism
FSN
Pattern:
Ribonucleic acid of X organism (substance)
For example,
Ribonucleic acid of Norovirus genogroup I (substance)
Preferred Term
Preferred Term (US/GB) with initial letter case sensitive:
Pattern:
X organism RNA
For example,
Norovirus genogroup I
Synonyms
Pattern: A synonym that matches FSN
For example,
Ribonucleic acid of Norovirus genogroup I
Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.
Exemplar
The following illustrates the stated and inferred view:
Modeling - Ribosomal ribonucleic acid of X organism
Parent concept
Most distal appropriate descendant of 118251005 | Microbial ribosomal ribonucleic acid (substance)|
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is Modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: < 726711005 |Disposition (disposition)|
While the allowed range is broader, substance concepts should only use <726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..*
Naming - Ribosomal ribonucleic acid of X organism
FSN
Pattern:
Ribosomal ribonucleic acid of X organism (substance)
For example,
Ribosomal ribonucleic acid of Candida (substance)
Preferred Term
Preferred Term, with Initial letter case sensitive.
Pattern:
X organism rRNA
For example,
Candida rRNA
Synonyms
Pattern:
A synonym that matches FSN
For example,
Ribosomal ribonucleic acid of Candida
Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.
Exemplar
The following illustrates the stated and inferred view:
Modeling - Messenger ribonucleic acid of X organism
Parent concept
Most distal appropriate descendant of 69908008 |Messenger ribonucleic acid (substance)|
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: <726711005|Disposition (disposition)
While the allowed range is broader, substance concepts should only use <726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..*
Naming - Messenger ribonucleic acid of X organism
FSN
Pattern: Messenger ribonucleic acid of X organism (substance)
For example,
Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2 (substance)
Preferred Term
Preferred Term, with Initial letter case sensitive.
Pattern: X organism mRNA
For example,
SARS-CoV-2 mRNA
Synonyms
Pattern: A synonym that matches FSN
For example,
Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2
Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.
Exemplar
Stated and inferred view of 1119343008 |Messenger ribonucleic acid of severe acute respiratory syndrome coronavirus 2 (substance)|:
Modeling - Messenger ribonucleic acid of X organism encoding for specific protein
Parent concept
Most distal appropriate descendant of 69908008 |Messenger ribonucleic acid (substance)|
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: <726711005 |Disposition (disposition)|
While the allowed range is broader, substance concepts should only use <726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..*
Naming - Messenger ribonucleic acid of X organism encoding for specific protein
FSN
Pattern: Messenger ribonucleic acid of X organism encoding for protein Y (substance)
For example,
Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2 encoding spike protein (substance)
Preferred Term
Preferred Term, with Initial letter case sensitive.
Pattern: X organism mRNA encoding for protein Y
For example,
SARS-CoV-2 mRNA encoding spike protein
Synonyms
Pattern: A synonym that matches FSN
For example,
Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2 encoding spike protein (substance)
Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.
Exemplar
Stated and inferred view of 1155866009 |Messenger ribonucleic acid of severe acute respiratory syndrome coronavirus 2 encoding spike protein (substance)|.
Modeling - Deoxyribonucleic acid of X organism
Parent concept
Most distal appropriate descendant of 118249006 |Microbial deoxyribonucleic acid (substance)|
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: <726711005 |Disposition (disposition)
While the allowed range is broader, substance concepts should only use <726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..*
Naming - Deoxyribonucleic acid of X organism
FSN
Pattern: Deoxyribonucleic acid of X organism (substance)
For example,
Deoxyribonucleic acid of Aspergillus terreus (substance)
Preferred Term
Preferred Term (US/GB), with Initial letter case sensitive:
Pattern: X organism DNA
For example,
Aspergillus terreus DNA
Synonyms
Pattern: A synonym that matches FSN
For example,
Deoxyribonucleic acid of Aspergillus terreus
Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.
Exemplar
The following illustrates the stated and inferred view:
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