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Fractionated and unfractionated substances

This Editorial Guide is used for Education Purposes Only. It is used in the Authoring Courses and Certifications. It is based on the January 2026 Editorial Guide.

Substance concepts that contain terms such as “fractionated” or “unfractionated” are not created in the Substance hierarchy. "Unfractinated" should not be included when referring to the "entire substance" or "whole substance"; it is implied. "Fractionated" usually refers to a separation technique or process.

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