Terminology Binding Examples
Colorectal Cancer Resection Reporting Protocol
Below is a section of the International Collaboration on Cancer Reporting (ICCR) Colorectal Cancer Resection reporting protocol. This page exemplifies some of the bindings for this data set, namely the data elements for 'histological tumor type' and 'lymph node status'. Similar binding exists for each question/answer set within the protocol. View an excerpt from the ICCR Colorectal Cancer Histopathology Reporting Protocol:
Binding of Histological Tumor Type
The diagram below shows the question and options for the 'histological tumor type' data element. The Observable entity to be measured/assessed is "Histological tumour type", which is represented by the SNOMED CT concept 1284862009 |Histologic type of primary malignant neoplasm of cecum and/or colon and/or rectum (observable entity)| and represents the "question" being answered. The possible "answers" or observations are listed in the table below with associated SNOMED CT concept bindings for each histology option.

Data Item: HISTOLOGICAL TUMOR TYPE
Question
Type: Question
Cardinality: 1..1
Display: Histological tumor type
Binding: 1284862009 |Histologic type of primary malignant neoplasm of cecum and/or colon and/or rectum (observable entity)|
Response options (Group)
Cardinality: 0..1
Options:
No evidence of residual tumour
Adenocarcinoma not otherwise specified (NOS) – 1187332001 |Adenocarcinoma (morphologic abnormality)|
Mucinous adenocarcinoma – 72495009 |Mucinous adenocarcinoma (morphologic abnormality)|
Signet-ring cell adenocarcinoma – 87737001 |Signet ring cell carcinoma (morphologic abnormality)|
Medullary carcinoma – 32913002 |Medullary carcinoma (morphologic abnormality)|
Serrated adenocarcinoma – 450948005 |Serrated adenocarcinoma (morphologic abnormality)|
Micropapillary adenocarcinoma – 450895005 |Micropapillary carcinoma (morphologic abnormality)|
Adenoma-like adenocarcinoma – 28558000 |Villous adenocarcinoma (morphologic abnormality)|
Neuroendocrine carcinoma, small cell type – 719105002 |Small cell neuroendocrine carcinoma (morphologic abnormality)|
Neuroendocrine carcinoma, large cell type – 128628002 |Large cell neuroendocrine carcinoma (morphologic abnormality)|
Mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) – 785766008 |Mixed neuroendocrine-non neuroendocrine neoplasm (morphologic abnormality)|
Other, specify
Binding of Lymph Node Status
The diagram below shows the question and options for the 'lymph node status' data element. The Observable entity to be measured/assessed is "Lymph node status", which is represented by the SNOMED CT concept 1268302004 |Presence of metastatic neoplasm in lymph node in excised tissue specimen (observable entity)| and represents the "question" being answered. The possible "answers" or observations are listed in the table below with associated SNOMED CT concept bindings for each option.

Question 1: Lymph node status
Type: Question
Cardinality: 1..1
Display: Lymph node status
Binding: 1268302004 |Presence of metastatic neoplasm in lymph node in excised tissue specimen (observable entity)|
Response options (Group):
Cannot be assessed – 1156316003 |Cannot be determined (qualifier value)|
No nodes submitted or found – 385432009 |Not applicable (qualifier value)|
Not involved – 47492008 |Not seen (qualifier value)|
Involved – 52101004 |Present (qualifier value)|
Question 2: Number of lymph nodes examined
Type: Question
Cardinality: 1..1
Display: Number of lymph nodes examined
Binding: 444025001 |Number of lymph nodes examined by microscopy in excised specimen (observable entity)|
Response value:
1..1 — Not a SNOMED Value
Question 3: Number of involved lymph nodes examined
Type: Question
Cardinality: 1..1
Display: Number of involved lymph nodes examined
Binding: 443527007 |Number of lymph nodes containing metastatic neoplasm in excised specimen (observable entity)|
Response value:
1..1 — Not a SNOMED Value
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