Pharmaceutical Dose Form Grouper Without Basic Dose Form

Overview

Pharmaceutical dose form grouper concepts that do not include a basic dose form but are deemed to be clinically useful and that can be sufficiently defined will be included in the 736542009 |Pharmaceutical dose form (dose form)| hierarchy.

Modeling

Grouper concepts concepts that do not include a basic dose form shall be modeled using the proximal primitive modeling pattern.

Semantic tag

(dose form)

Definition status

Defined

Exception:

Grouper concepts representing drug delivery systems will have a definition status of Primitive

Attribute:

Has dose form release characteristic

Range: << 736480007 |Dose form release characteristic (release characteristic)|

Cardinality: 0..*

While the allowed range is broader, the grouper concepts without basic dose form should have 1..1 |Has dose form release characteristic| attributes.

Attribute:

Has dose form intended site

Range: << 736479009 |Dose form intended site (intended site)

Cardinality: 0..*

While the allowed range is broader, the grouper concepts without basic dose form should have 1..* |Has dose form intended site| attributes.

Attribute:

Has dose form administration method

Range: << 736665006 |Dose form administration method (administration method)

Cardinality: 0..*

While the allowed range is broader, the grouper concepts without basic dose form should have 1..1 |Has dose form administration method| attributes.

Naming

FSN

For concepts with 736472000 |Has dose form administration method (attribute)| = 738996007 |Spray (administration method)|, use the following pattern for the FSN; align naming and case sensitivity with the FSN for the concept that is selected as the attribute value. For multiple intended sites, the intended sites must be in alphabetical order and separated by the word “and”.

<Dose form release characteristic> <Dose form intended site FSN> <Dose form administration method> (dose form)

For example,

Conventional release cutaneous spray (dose form)
Conventional release nasal spray (dose form)
Conventional release sublingual spray (dose form)

For concepts representing drops with 736472000 |Has dose form administration method (attribute)| = 738994005 |Instill (administration method)|, use the following pattern for the FSN; align naming and case sensitivity with the FSN for the concept that is selected as the attribute value. For multiple intended sites, the intended sites must be in alphabetical order and separated by the word “and”.

<Dose form release characteristic> <Dose form intended site FSN> <Dose form administration method> (dose form)

For example,

Conventional release nasal drops (dose form)
Prolonged-release eye drops (dose form)

For concepts representing drug delivery systems, use the following pattern for the FSN; align naming and case sensitivity with the FSN for the concept that is selected as the attribute value. For multiple intended sites, the intended sites must be in alphabetical order and separated by the word “and”.

<Dose form release characteristic> <Dose form intended site FSN> drug delivery system

For example,

Prolonged-release intrauterine drug delivery system (dose form)
Prolonged-release transdermal drug delivery system (dose form)

Preferred Term

For concepts with 736472000 |Has dose form administration method (attribute)| = 738996007 |Spray (administration method)|, use the following pattern for the PT; align naming and case sensitivity with the PT for the concept that is selected as the attribute value. For multiple intended sites, the intended sites must be in alphabetical order and separated by the word “and”. Exclude <Dose form release characteristic> when = 736849007 |Conventional release (release characteristic)|.

<Dose form release characteristic> <Dose form intended site FSN> <Dose form administration method>

For example,

Cutaneous spray
Nasal spray
Sublingual spray

For concepts representing drops with 736472000 |Has dose form administration method (attribute)| = 738994005 |Instill (administration method)|, use the following pattern for the PT; align naming and case sensitivity with the PT for the concept that is selected as the attribute value. For multiple intended sites, the intended sites must be in alphabetical order and separated by the word “and”. Exclude <Dose form release characteristic> when = 736849007 |Conventional release (release characteristic)|.

<Dose form release characteristic> <Dose form intended site FSN> <Dose form administration method>

For example,

Nasal drops
Prolonged-release eye drops

For concepts representing drug delivery systems, use the following pattern for the PT; align naming and case sensitivity with the PT for the concept that is selected as the attribute value. For multiple intended sites, the intended sites must be in alphabetical order and separated by the word “and”. Exclude <Dose form release characteristic> when = 736849007 |Conventional release (release characteristic)|.