# Continuous presentation: Metered dose unit of presentation

*Examples: various inhalers, nasal sprays, some cutaneous sprays/foams*

The unit of presentation is the actuation, the “single operation of a metered-dose pump, valve or other equivalent dosing mechanism” \[EDQM].

Strength is expressed as “per one unit of presentation” and the presentation strength and the concentration are exactly the same.

### Example: Single inhaler containing a total of 200 actuations worth of salbutamol, 100 micrograms per actuation, packaged in a box

<figure><img src="https://4060284305-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FuoSxuN6wQMDYcvuq2wNX%2Fuploads%2F4rxV7Zu7hwqejWLU5Wtb%2FScreenshot%202025-09-26%20at%202.57.50%E2%80%AFPM.png?alt=media&#x26;token=1e755a29-113b-4da1-b7d0-9d05a7a7c7d0" alt=""><figcaption></figcaption></figure>

<figure><img src="https://github.com/SNOMED-Documents/snomed-editorial-guide/blob/main/authoring/pharmaceutical-and-biologic-product/images/304775951.jpg" alt=""><figcaption></figcaption></figure>

| Manufactured dose form          | Solution for aerosolisation        |                                                                                                                                                                                     |
| ------------------------------- | ---------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
| Unit of presentation            | Actuation                          |                                                                                                                                                                                     |
| \[Pack size]                    | 200 actuations in the inhaler      |                                                                                                                                                                                     |
| Precise active ingredient       | salbutamol sulphate                |                                                                                                                                                                                     |
| Basis of strength substance     | salbutamol                         |                                                                                                                                                                                     |
| Presentation strength (logical) | 100 mcg per 1 unit of presentation |                                                                                                                                                                                     |
| Presentation strength           | 100 mcg per 1 actuation            | UCUM: 100 mcg per 1 each                                                                                                                                                            |
| Concentration strength          |                                    | The concentration of salbutamol sulphate in the inhalant solution inside the inhaler container is probably known to the regulatory agency but is not deemed clinically significant. |

<a href="https://docs.google.com/forms/d/e/1FAIpQLScTmbZIf0UEQwYDkY27EEWBkaiYkHSbR0_9DmFrMLXoQLyL7Q/viewform?usp=pp_url&#x26;entry.1767247133=SCT+Editorial+Guide&#x26;entry.670899847=Continuous%20presentation%3A%20Metered%20dose%20unit%20of%20presentation" class="button primary">Provide Feedback</a>