# Continuous presentation: unbounded by container
*Examples: bulk powders and granules, bulk liquids, semi-solids*
These presentations are not particularly bound by their container in any way that is meaningful in terms of their use or administration; the Manufactured Item is a continuous presentation and almost all are used in individually calculated and variable amounts.
For example,
* Hydrocortisone cream for cutaneous use is contained in a tube, but its use is based on how much is squeezed out and applied to the skin.
* Chloramphenicol eye drops are presented in a dropper bottle, but they are administered drop by drop and although the dropper bottle aims to deliver a roughly uniform sized drop to the eye, they are not "metered dose containers" in the way that containers with valves are.
A unit of presentation is not usually given for these products. The pack size (not relevant for SNOMED international model) is given as the Manufactured Item quantity.\
Strength is expressed as a concentration and as such the presentation strength and the concentration are exactly the same.
### **Example: A 30g tube of hydrocortisone 1% cutaneous cream w/w in an outer box**
| Manufactured dose form | Cutaneous cream | |
| ------------------------------- | ---------------------------------- | ------------------------------------------------------------------------------------------- |
| Unit of presentation | NOT VALUED | There is nothing that really "bounds" the dose form that delivers the medication "per dose" |
| \[Pack size] | 30 g in the tube,1 tube in the box | |
| Precise active ingredient | hydrocortisone | |
| Basis of strength substance | hydrocortisone | |
| Presentation strength (logical) | 300 mg per 30 g | Not a clinically safe or recognisable expression of strength |
| Presentation strength | | |
| Concentration strength | 10 mg per 1 g | Synonym: 1.0 % w/w |
### **Example: A bottle of 5 mL of chloramphenicol eye drops 0.5% w/v in an outer box**
| Manufactured dose form | Eye drops, solution | |
| ------------------------------- | ---------------------------------------------- | ------------------------------------------------------------------------------------------- |
| Unit of presentation | NOT VALUED | There is nothing that really "bounds" the dose form that delivers the medication "per dose" |
| \[Pack size] | 5 ml in the dropper bottle,1 bottle in the box | |
| Precise active ingredient | chloramphenicol | |
| Basis of strength substance | chloramphenicol | |
| Presentation strength (logical) | 25 mg per 5 mL | Not a clinically safe or recognisable expression of strength |
| Presentation strength | | |
| Concentration strength | 5 mg per 1 mL | Synonym: 0.5 % w/v |
### **Example: A pack of 500g of sterculia 62% w/w granules (EDQM –"granules" = "oral granules")**
| Manufactured dose form | Oral granules | |
| ------------------------------- | ---------------- | ------------------------------------------------------------------------------------------- |
| Unit of presentation | NOT VALUED | There is nothing that really "bounds" the dose form that delivers the medication "per dose" |
| \[Pack size] | 500 g in the box | |
| Precise active ingredient | sterculia | |
| Basis of strength substance | sterculia | |
| Presentation strength (logical) | 310 g per 500 g | Not a clinically safe or recognisable expression of strength |
| Presentation strength | | |
| Concentration strength | 620 mg per 1 g | Synonym: 62 % w/w |
### **Example: A bottle of 60 mL of digoxin oral solution 50mcg/mL in an outer box (which has an oral syringe in it)**
| Manufactured dose form | Oral solution | |
| ------------------------------- | ---------------------------------------- | ------------------------------------------------------------------------------------------- |
| Unit of presentation | NOT VALUED | There is nothing that really "bounds" the dose form that delivers the medication "per dose" |
| \[Pack size] | 60 ml in the bottle, 1 bottle in the box | |
| Precise active ingredient | digoxin | |
| Basis of strength substance | digoxin | |
| Presentation strength (logical) | 3 mg per 60 mL | Not a clinically safe or recognisable expression of strength |
| Presentation strength | | |
| Concentration strength | 50 mcg per 1 mL | Synonym: 0.5 % w/v |
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