> For the complete documentation index, see [llms.txt](https://docs.snomed.org/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.snomed.org/snomed-ct-specifications/snomed-ct-editorial-guide/readme/authoring/domain-specific-modeling/substance/substance-naming-and-modeling-conventions/guidelines-for-specific-substance-types/deoxyribonucleic-acid-and-ribonucleic-acid.md).

# Deoxyribonucleic acid and ribonucleic acid

## Ribonucleic acid of X organism

### Modeling

<table data-header-hidden><thead><tr><th width="201.51171875">Parent concept</th><th>Most distal appropriate descendant of 118248003 |Microbial ribonucleic acid (substance)|</th></tr></thead><tbody><tr><td><strong>Parent concept</strong></td><td>Most distal appropriate descendant of 118248003 |Microbial ribonucleic acid (substance)|</td></tr><tr><td><strong>Semantic tag</strong></td><td>(substance)</td></tr><tr><td><strong>Definition status</strong></td><td>Primitive</td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Is modification of</strong></p></td><td><p>Range &#x3C;105590001 |Substance (substance)|</p><p>Cardinality: 0..*</p><p>One relationship to be created to represent each modified component of the substance</p></td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Has disposition</strong></p></td><td><p>Range: &#x3C;726711005 |Disposition (disposition)|</p><ul><li>While the allowed range is broader, substance concepts should only use &#x3C;726711005 |Disposition (disposition)| as the attribute value.</li></ul><p>Cardinality: 0..*</p></td></tr></tbody></table>

### Naming

#### FSN

Pattern:

* Ribonucleic acid of X organism (substance)

For example,

* Ribonucleic acid of Norovirus genogroup I (substance)

***

#### Preferred Term

Preferred Term (US/GB) with initial letter case sensitive:

Pattern:

* X organism RNA

For example,

* Norovirus genogroup I

***

#### Synonyms

Pattern: A synonym that matches FSN

For example,

* Ribonucleic acid of Norovirus genogroup I

Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.

### Exemplar

The following illustrates the **stated** and **inferred** view:

<div align="left"><figure><img src="/files/qRRsRWYuElZn2A5jUlQp" alt=""><figcaption></figcaption></figure></div>

<figure><img src="https://github.com/SNOMED-Documents/snomed-editorial-guide/blob/main/authoring/substance/images/174691563.png" alt=""><figcaption></figcaption></figure>

## Ribosomal ribonucleic acid of X organism

### Modeling

<table data-header-hidden><thead><tr><th width="206.515625"></th><th></th></tr></thead><tbody><tr><td><strong>Parent concept</strong></td><td>Most distal appropriate descendant of 118251005 | Microbial ribosomal ribonucleic acid (substance)|</td></tr><tr><td><strong>Semantic tag</strong></td><td>(substance)</td></tr><tr><td><strong>Definition status</strong></td><td>Primitive</td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Is Modification of</strong></p></td><td><p>Range &#x3C;105590001 |Substance (substance)|</p><p>Cardinality: 0..*</p><p>One relationship to be created to represent each modified component of the substance</p></td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Has disposition</strong></p></td><td><p>Range: &#x3C; 726711005 |Disposition (disposition)|</p><ul><li>While the allowed range is broader, substance concepts should only use &#x3C;726711005 |Disposition (disposition)| as the attribute value.</li></ul><p>Cardinality: 0..*</p></td></tr></tbody></table>

### Naming

#### FSN

Pattern:

* Ribosomal ribonucleic acid of X organism (substance)

For example,

* Ribosomal ribonucleic acid of Candida (substance)

***

#### Preferred Term

Preferred Term, with Initial letter case sensitive.

Pattern:

* X organism rRNA

For example,

* Candida rRNA

***

#### Synonyms

Pattern:

* A synonym that matches FSN

For example,

* Ribosomal ribonucleic acid of Candida

Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.

### Exemplar

The following illustrates the **stated** and **inferred** view:

<div align="left"><figure><img src="/files/BEIoAKpvvZxcTeIsntCA" alt=""><figcaption></figcaption></figure></div>

<figure><img src="https://github.com/SNOMED-Documents/snomed-editorial-guide/blob/main/authoring/substance/images/174691562.png" alt=""><figcaption></figcaption></figure>

## Messenger ribonucleic acid of X organism

### Modeling

<table data-header-hidden><thead><tr><th width="265.953125"></th><th></th></tr></thead><tbody><tr><td><strong>Parent concept</strong></td><td>Most distal appropriate descendant of 69908008 |Messenger ribonucleic acid (substance)|</td></tr><tr><td><strong>Semantic tag</strong></td><td>(substance)</td></tr><tr><td><strong>Definition status</strong></td><td>Primitive</td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Is modification of</strong></p></td><td><p>Range &#x3C;105590001 |Substance (substance)|</p><p>Cardinality: 0..*</p><p>One relationship to be created to represent each modified component of the substance</p></td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Has disposition</strong></p></td><td><p>Range: &#x3C;726711005|Disposition (disposition)</p><ul><li>While the allowed range is broader, substance concepts should only use &#x3C;726711005 |Disposition (disposition)| as the attribute value.</li></ul><p>Cardinality: 0..*</p></td></tr></tbody></table>

### Naming

#### FSN

Pattern: Messenger ribonucleic acid of X organism (substance)

For example,

* Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2 (substance)

***

#### Preferred Term

Preferred Term, with Initial letter case sensitive.

Pattern: X organism mRNA

For example,

* SARS-CoV-2 mRNA

***

#### Synonyms

Pattern: A synonym that matches FSN

For example,

* Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2

Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.

### Exemplar

Stated and inferred view of 1119343008 |Messenger ribonucleic acid of severe acute respiratory syndrome coronavirus 2 (substance)|:

<figure><img src="/files/LJh52p7MXOYdMdNEUCYA" alt=""><figcaption></figcaption></figure>

<figure><img src="https://github.com/SNOMED-Documents/snomed-editorial-guide/blob/main/authoring/substance/images/174691558.png" alt=""><figcaption></figcaption></figure>

## Messenger ribonucleic acid of X organism encoding for specific protein

### Modeling

<table data-header-hidden><thead><tr><th width="228.1171875"></th><th></th></tr></thead><tbody><tr><td><strong>Parent concept</strong></td><td>Most distal appropriate descendant of 69908008 |Messenger ribonucleic acid (substance)|</td></tr><tr><td><strong>Semantic tag</strong></td><td>(substance)</td></tr><tr><td><strong>Definition status</strong></td><td>Primitive</td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Is modification of</strong></p></td><td><p>Range &#x3C;105590001 |Substance (substance)|</p><p>Cardinality: 0..*</p><p>One relationship to be created to represent each modified component of the substance</p></td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Has disposition</strong></p></td><td><p>Range: &#x3C;726711005 |Disposition (disposition)|</p><ul><li>While the allowed range is broader, substance concepts should only use &#x3C;726711005 |Disposition (disposition)| as the attribute value.</li></ul><p>Cardinality: 0..*</p></td></tr></tbody></table>

### Naming

#### FSN

Pattern: Messenger ribonucleic acid of X organism encoding for protein Y (substance)

For example,

* Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2 encoding spike protein (substance)

***

#### Preferred Term

Preferred Term, with Initial letter case sensitive.

Pattern: X organism mRNA encoding for protein Y

For example,

* SARS-CoV-2 mRNA encoding spike protein

***

#### Synonyms

Pattern: A synonym that matches FSN

For example,

* Messenger ribonucleic acid of Severe acute respiratory syndrome coronavirus 2 encoding spike protein (substance)

Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.

### Exemplar

Stated and inferred view of 1155866009 |Messenger ribonucleic acid of severe acute respiratory syndrome coronavirus 2 encoding spike protein (substance)|:

<figure><img src="/files/wY8bgNNKgGrJUyDE8usZ" alt=""><figcaption></figcaption></figure>

<figure><img src="https://github.com/SNOMED-Documents/snomed-editorial-guide/blob/main/authoring/substance/images/174691557.png" alt=""><figcaption></figcaption></figure>

## Deoxyribonucleic acid of X organism

### Modeling

<table data-header-hidden><thead><tr><th width="191.31640625"></th><th></th></tr></thead><tbody><tr><td><strong>Parent concept</strong></td><td>Most distal appropriate descendant of 118249006 |Microbial deoxyribonucleic acid (substance)|</td></tr><tr><td><strong>Semantic tag</strong></td><td>(substance)</td></tr><tr><td><strong>Definition status</strong></td><td>Primitive</td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Is modification of</strong></p></td><td><p>Range &#x3C;105590001 |Substance (substance)|</p><p>Cardinality: 0..*</p><p>One relationship to be created to represent each modified component of the substance</p></td></tr><tr><td><p><strong>Attribute:</strong></p><p><strong>Has disposition</strong></p></td><td><p>Range: &#x3C;726711005 |Disposition (disposition)</p><ul><li>While the allowed range is broader, substance concepts should only use &#x3C;726711005 |Disposition (disposition)| as the attribute value.</li></ul><p>Cardinality: 0..*</p></td></tr></tbody></table>

### Naming

#### FSN

Pattern: Deoxyribonucleic acid of X organism (substance)

For example,

* Deoxyribonucleic acid of Aspergillus terreus (substance)

***

#### Preferred Term

Preferred Term (US/GB), with Initial letter case sensitive:

Pattern: X organism DNA

For example,

* Aspergillus terreus DNA

***

#### Synonyms

Pattern: A synonym that matches FSN

For example,

* Deoxyribonucleic acid of Aspergillus terreus

Additional synonyms (when a legitimate synonym exists for Organism name) are applicable.

### Exemplar

The following illustrates the **stated** and **inferred** view:

<figure><img src="/files/9raAoypDNRLhKYg4qOH2" alt=""><figcaption></figcaption></figure>

<figure><img src="https://github.com/SNOMED-Documents/snomed-editorial-guide/blob/main/authoring/substance/images/174691561.png" alt=""><figcaption></figcaption></figure>

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