Radioactive substances
Representation of radioactive isotopes
Modeling
Parent concept
Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)|
Most distal appropriate descendant of 33638001 |Isotope (substance)|
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: <726711005 |Disposition (disposition)|
NOTE: While the allowed range is broader, substance concepts should only use descendants of the concept 726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..1
Naming
Superscripts should not be used in either Fully Specified Name, Preferred Term, or synonyms.
FSN
Pattern:
[name of isotope]-[atomic number] (substance)
For example,
Gallium-67 (substance)
Preferred Term
Pattern:
[name of isotope]-[atomic number]
For example,
Gallium-67
Synonyms
Pattern:
[atomic number]-[chemical symbol]
For example,
67-Ga
Exemplar
The following illustrates the hierarchy view:
The following illustrates the stated and inferred view:
Representation of radioisotope with salt
Modeling
Parent concept
Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)|
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: <726711005 |Disposition (disposition) |
NOTE: While the allowed range is broader, substance concepts should only use <726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..1
Naming
Superscripts should not be used in either Fully Specified Name, Preferred Term, or synonyms.
Parentheses should be used to delineate the atomic number and chemical symbol from the rest of the terming; this aligns with INN.
FSN
Pattern: [name of isotope] ([atomic number]-[chemical symbol]) [salt] (substance)
For example,
Gallium (67-Ga) citrate (substance
Preferred Term
Pattern: [name of isotope] ([atomic number]-[chemical symbol]) [salt]
For example,
Gallium (67-Ga) citrate
Exemplar - radioisotope with salt
The following illustrates the stated and inferred view:
Representation of combined radioisotope substances
Modeling
Parent concept
Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)| and a second parent identifying the labeled component
Semantic tag
(substance)
Definition status
Primitive
Attribute:
Is modification of
Range <105590001 |Substance (substance)|
Cardinality: 0..*
One relationship to be created to represent each modified component of the substance
Attribute:
Has disposition
Range: <726711005 |Disposition (disposition) |
While the allowed range is broader, substance concepts should only use <726711005 |Disposition (disposition)| as the attribute value.
Cardinality: 0..1
Naming
Superscripts should not be used in either Fully Specified Name, Preferred Term, or synonyms.
The Fully Specified Name should explicitly state that a component was “labeled” by a radioisotope in the FSN. Do not use “with”, “and”, or “tagged”.
Omit the word “labeled” from the PT; keep a synonym to match the FSN.
Exemplar - combined radioisotope substances
The following illustrates both the stated and inferred view:
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