Exclusions, Modifiers, and Comorbidities
Exclusions
Exclusion guidelines from WHO coding publications will be evaluated as a last step in mapping context evaluation.
Review of modifiers
There are two types of modifiers which appear in the ICD-10 Alphabetical Index: essential and non-essential.
Non-essential modifiers appear in parentheses following the terms they modify and do not affect the target code selection for a given condition, sign or symptom but are considered as alternatives to the expression of the term.
The map specialist will review the ICD-10 Alphabetical Index to identify any essential modifiers which represent SNOMED CT concepts that are descendants of:
the source concept to be mapped, or
the source concept etiology SNOMED CT code when dagger and asterisk guidance requires a separate target for cause of the disorder. The Map Terminologist will add new Map members with the associated target specific to the alpha reference as context dependent maps with a mapRule.
Mapping for concepts of poisoning and overdose will require analysis of the Alphabetic Index's Table of Drugs and Chemicals. This table organizes drugs or chemicals along with the corresponding codes for adverse situations including accidental events, intentional self-harm, poisoning of undetermined intent, and adverse effects in therapeutic use. This table also may include essential modifiers which require attention for possible exclusion rules. For example, when mapping the SNOMED CT source concept 295830007 | Overdose of antidepressant drug (disorder)| a review of the drugs table will expose these entries for antidepressant poisoning:

In this case, the default target code for mapping of antidepressant poisoning is T43.2 for mapGroup one and X41 for mapGroup two based upon WHO advice to assume accidental poisoning when intent is unspecified. Note that essential modifiers are listed for MAO inhibitors, triazolpyridine, and tricyclic or tetracyclic antidepressants, which have potential to change the codes assigned.
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