> For the complete documentation index, see [llms.txt](https://docs.snomed.org/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.snomed.org/snomed-ct-specifications/snomed-ct-expression-constraint-language/appendices/appendix-a-examples-of-valid-expressions/a2-refinements-valid-expressions.md).

# Refinements - Valid Expressions

<table data-full-width="true"><thead><tr><th width="306.8046875">Expression Constraint</th><th width="177.5546875">Precoordinated</th><th>Postcoordinated</th></tr></thead><tbody><tr><td>&#x3C; 19829001 |Disorder of lung| : 116676008 |Associated morphology| = 79654002 |Edema|</td><td>11468004 | Postoperative pulmonary edema|</td><td>210051003 |Injury to heart and lung| : 116676008 |Associated morphology| = 79654002 |Edema| 276637009 | Hemorrhagic pulmonary edema|</td></tr><tr><td>&#x3C; 19829001 |Disorder of lung| : 116676008 |Associated morphology| = &#x3C;&#x3C; 79654002 |Edema|</td><td>233709006 | Toxic pulmonary edema|</td><td>275504005 |Lung cyst| : 116676008 |Associated morphology| = 103619005 |Inflammatory edema| 233711002 | Oxygen-induced pulmonary edema|</td></tr><tr><td>19829001 |Disorder of lung| : 116676008 |Associated morphology| = 40829002 |Acute edema|</td><td><em>(none)</em></td><td><em>(none)</em></td></tr><tr><td>&#x3C; 404684003 |Clinical finding| : 363698007 |Finding site| = &#x3C;&#x3C; 39057004 |Pulmonary valve structure| , 116676008 |Associated morphology| = &#x3C;&#x3C; 415582006 |Stenosis|</td><td>56786000 | Pulmonic valve stenosis|</td><td>56786000 |Pulmonic valve stenosis| : 363698007 |Finding site| = 90318009 |Structure of anulus fibrosus of pulmonary artery| , 116676008 |Associated morphology| = 88015002 |Partial stenosis| 86299006 | Tetralogy of Fallot|</td></tr><tr><td>404684003 |Clinical finding| : 363698007 |Finding site| = 39057004 |Pulmonary valve structure| , 116676008 |Associated morphology| = 415582006 |Stenosis|</td><td><em>(none)</em></td><td><em>(none)</em></td></tr><tr><td>* : 246075003 |Causative agent| = 387517004 |Paracetamol|</td><td>295124009 | Paracetamol overdose|</td><td>404684003 |Clinical finding| : 246075003 |Causative agent| = 387517004 |Paracetamol| 292042007 | Adverse reaction to paracetamol|</td></tr><tr><td>&#x3C; 404684003 |Clinical finding| : { 363698007 |Finding site| = &#x3C;&#x3C; 39057004 |Pulmonary valve structure| , 116676008 |Associated morphology| = &#x3C;&#x3C; 415582006 |Stenosis| }, { 363698007 |Finding site| = &#x3C;&#x3C; 53085002 |Right ventricular structure| , 116676008 |Associated morphology| = &#x3C;&#x3C; 56246009 |Hypertrophy| }</td><td>86299006 | Tetralogy of Fallot|</td><td>404684003 |Clinical finding| : { 363698007 |Finding site| = 31689007 |Structure of cusp of pulmonic valve| , 116676008 |Associated morphology| = 415582006 |Stenosis| }, { 363698007 |Finding site| = 53085002 |Right ventricular structure| , 116676008 |Associated morphology| = 125521000 |Acute hypertrophy| } 204351007 | Fallot’s trilogy|</td></tr><tr><td>&#x3C;&#x3C; 404684003 |Clinical finding| : &#x3C;&#x3C; 47429007 |Associated with| = &#x3C;&#x3C; 267038008 |Edema|</td><td>230580009 | Myxedema neuropathy|</td><td>95356008 |Mucosal ulcer| : 42752001 |Due to| = 19242006 |Pulmonary edema|</td></tr><tr><td>&#x3C; 27658006 |Amoxicillin| : 411116001 |Has dose form| = &#x3C;&#x3C; 385055001 |Tablet dose form| , { 179999999100 |Has basis of strength| = ( 219999999102 |Amoxicillin only| : 189999999103 |Has strength magnitude| >= #200, 199999999101 |Has strength unit| = 258684004 |mg| )}</td><td>374644001 | Amoxicillin trihydrate 200 mg tablet|</td><td>27658006 |Amoxicillin| : 411116001 |Has dose form| = 421026006 |Oral tablet| , { 127489000 |Has active ingredient| = 96068000 |Amoxicillin trihydrate| , 179999999100 |Has basis of strength| = ( 219999999102 |Amoxicillin only| : 189999999103 |Has strength magnitude| = #500, 199999999101 |Has strength unit| = 258684004 |mg| )}</td></tr><tr><td>&#x3C; 27658006 |Amoxicillin| : 411116001 |Has dose form| = &#x3C;&#x3C; 385055001 |Tablet dose form| , { 179999999100 |Has basis of strength| = ( 219999999102 |Amoxicillin only| : 189999999103 |Has strength magnitude| >= #500, 189999999103 |Has strength magnitude| &#x3C;= #800, 199999999101 |Has strength unit| = 258684004 |mg| )}</td><td>374646004 | Amoxicillin 500 mg tablet|</td><td>27658006 |Amoxicillin| : 411116001 |Has dose form| = 421026006 |Oral tablet| , { 179999999100 |Has basis of strength| = ( 219999999102 |Amoxicillin only| : 189999999103 |Has strength magnitude| = #750, 199999999101 |Has strength unit| = 258684004 |mg| )}</td></tr><tr><td>&#x3C; 373873005 |Pharmaceutical / biologic product| : 209999999104 |Has trade name| = “PANADOL”</td><td>259999999103 | PANADOL [paracetamol] tablet|</td><td>373873005 |Pharmaceutical / biologic product| : { 127489000 |Has active ingredient| = 412031009 |Paracetamol or derivative| }, 209999999104 |Has trade name| = “PANADOL”</td></tr><tr><td>&#x3C; 91723000 |Anatomical structure| : R 363698007 |Finding site| = &#x3C; 125605004 |Fracture of bone|</td><td>85050009 | Humerus|</td><td>85050009 |Humerus| : 272741003 |Laterality| = 7771000 |Left| 71341001 | Femur| 71341001 |Femur| : 272741003 |Laterality| = 24028007 |Right|</td></tr><tr><td>&#x3C; 125605004 |Fracture of bone| . 363698007 |Finding site|</td><td>85050009 | Humerus|</td><td>85050009 |Humerus| : 272741003 |Laterality| = 7771000 |Left| 71341001 | Femur| 71341001 |Femur| : 272741003 |Laterality| = 24028007 |Right|</td></tr><tr><td>&#x3C; 105590001 |Substance| : R &#x3C;&#x3C; 127489000 |Has active ingredient| = &#x3C; 27658006 |Product containing amoxicillin|</td><td>395938000 | Clavulanate potassium|</td><td>387137007 | Omeprazole|</td></tr><tr><td>&#x3C; 27658006 |Product containing amoxicillin| . &#x3C;&#x3C; 127489000 |Has active ingredient|</td><td>395938000 | Clavulanate potassium|</td><td>387137007 | Omeprazole|</td></tr><tr><td>&#x3C; 404684003 |Clinical finding| : * = 79654002 |Edema|</td><td>19242006 | Pulmonary edema|</td><td>404684003 |Clinical finding| : 116676008 |Associated morphology| = 79654002 |Edema| 97341000119105 Proliferative retinopathy with retinal edema due to type</td></tr><tr><td>&#x3C; 404684003 |Clinical finding| : 116676008 |Associated morphology| = *</td><td>19242006 | Pulmonary edema|</td><td>404684003 |Clinical finding| : 116676008 |Associated morphology| = 79654002 |Edema| 263225007 | Hip fracture| 404684003 |Clinical finding| : 116676008 |Associated morphology| = 72704001 |Fracture|</td></tr></tbody></table>

{% hint style="info" %}
Please note that some of these examples are based on a hypothetical drug concept model. These examples are not intended to reflect any specific drug model.

SNOMED CT identifiers with the '9999999' namespace were created for example only, and should not be used in a production environment.
{% endhint %}

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