Groupers Based on Multiple Dispositions, Structures
Overview
Groupers comprised of two or more existing disposition and/or structure groupers that can be sufficiently defined may be included in the |Medicinal product| hierarchy. High-level grouper concepts support the organization of the combined groupers based on disposition and/or structure:
766779001 |Medicinal product categorized by disposition (product)|
763760008 |Medicinal product categorized by structure (product)|
For some medicinal products, their clinical usefulness is related to the combination of both their structure and their disposition; it is the structure that produces the disposition.
For example,
Clemastine is a substance whose anti-histamine behaviour is based upon its structure being ethanolamine derived.
Since structure-based grouping and disposition are characteristics of the active ingredient substance(s) present in the medicinal product, combined 'structure and disposition grouping' concepts are inferred by the classifier to medicinal products and include all their child concepts (medicinal product form and clinical drug concepts), although in a browser, the inferred grouping concepts are shown on the proximal concept only (the "medicinal product containing" concept).
Modeling
Stated parent concept
763158003 |Medicinal product (product)
Semantic tag
(product)
Definition status
Defined
Attribute:
Has active ingredient
Range: <<105590001
Naming
FSN
Use the following pattern for the FSN if the combined grouper is comprised of two dispositions or two structural groupers; align naming and case significance with the PT as described in Section 4.1 and 4.2, respectively. The active ingredients must be in alphabetical order and separated by the word “and”.
Product containing <Active ingredient PT> and <Active ingredient PT> (product)
For example,
Product containing norepinephrine reuptake inhibitor and serotonin reuptake inhibitor (product)
Use the following pattern for the FSN if the combined grouper is comprised of one disposition and one structural grouper; align naming and case significance with the FSN for the concept with the FSN as described in Section 4.1 and 4.2, respectively.
Product containing <Structural grouper active ingredient PT> and <Disposition grouper active ingredient PT> (product)
For example,
Product containing piperazine derivative and histamine receptor antagonist (product)
Preferred Term
Use the following pattern for the FSN if the combined grouper is comprised of two dispositions or two structural groupers; align naming and case significance with the PT as described in Section 4.1 and 4.2, respectively. The active ingredients must be in alphabetical order and separated by the word “and”.
Product containing <Active ingredient PT> and <Active ingredient PT> (product)
For example,
Product containing norepinephrine reuptake inhibitor and serotonin reuptake inhibitor (product)
Use the following pattern for the FSN if the combined grouper is comprised of one disposition and one structural grouper; align naming and case significance with the FSN for the concept with the FSN as described in Section 4.1 and 4.2, respectively.
Product containing <Structural grouper active ingredient PT> and <Disposition grouper active ingredient PT> (product)
For example,
Product containing piperazine derivative and histamine receptor antagonist (product)
Synonym
Synonyms matching the FSN are not required.
Exemplars
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